Nick Read leads the Fungal Cell Biology Research Group in the Institute of Cell Biology and is a member of the Centre for Synthetic and Systems Biology (Synthys) at the University of Edinburgh. His research is on spore germination and the early stages of colony establishment and infection by filamentous fungi. The main organisms studied in his lab are the fungal model Neurospora crassa and the human pathogens Aspergillus fumigatus and Fusarium oxysporum. Current projects in his lab include:
· Calcium signalling during the early stages of colony establishment and infection
· Signalling during hyphal network formation
· Modes-of-action of antifungal peptides
Much of the research involves analysing living cells using a wide range of advanced imaging techniques and quantitative measurements and screens involving high throughput, multiparameter, live-cell assays. His group is integrating these live-cell techniques with genetical and physiological studies, with emphasis on interdisciplinary research and systems biology.